Training at JULABO
JULABO regularly offers product training for users of their products. The aim is to provide solutions to problems and a continuance to optimize the work, associated with JULABO units. If required, training can be organised directly with the customer.

Those interested in training or finding out more, please contact:
Mark Bitterwolf, markb@julabo.de (international)
Hans Faisst, h.faisst@julabo.de (German speaking area)

Bruker BioSciences Announces Post-Merger Restructuring; Company to Consolidate Certain Production Sites While Strengthening Sales and Customer Support
BILLERICA, Mass.--(BUSINESS WIRE)--Oct. 20, 2003--Bruker BioSciences Corporation (NASDAQ:BRKR) today announced a plan to consolidate two of its smaller production facilities with existing larger production facilities in the U.S. and Europe. This restructuring has already been partially implemented and is expected to be finalized in the second quarter of 2004.
Following the July 1st, 2003 merger of Bruker Daltonics and Bruker AXS, Bruker BioSciences has analyzed additional opportunities to drive its operating performance. The restructuring plan announced here goes beyond the original merger plan, and reflects the Company's commitment to cost-cutting and bottom-line improvement.
As part of the restructuring, the Bruker AXS business will consolidate its life sciences x-ray systems production in Madison, Wisconsin (USA), and will outsource or transfer to its other production centers the manufacturing of certain Bruker-Nonius technologies. Bruker-Nonius, a subsidiary of Bruker AXS located in Delft, The Netherlands, will strengthen its focus on applications and product development for life science x-ray crystallography and structural proteomics, as well as on marketing and customer support.
In addition, the Bruker Daltonics business will phase out manufacturing of substance detection products at its Faellanden, Switzerland site by the end of the second quarter of 2004. Due to this overall manufacturing consolidation, Bruker BioSciences expects to improve its operating performance by $2.5-3.0 million p.a. pre-tax, beginning in the third quarter of 2004.
Bruker BioSciences incurred associated restructuring costs of approximately $2.7 million in the third quarter of 2003, including non-cash charges for the write-down of goodwill and intangible assets of $1.2 million. These restructuring costs are separate from any anticipated special charges which were previously discussed in our S-4 filing in connection with the merger, including merger charges for acquired research and development, merger related costs and impairment of acquired assets.
"With the completion of the merger, we are pushing forward with a number of initiatives designed to further drive our top- and bottom-line growth," said Frank Laukien, President and CEO of Bruker BioSciences. "Beyond the merger synergies that we had discussed previously, we saw an opportunity for additional cost savings by improving our overall manufacturing efficiency. At the same time, we continue to gradually expand our global sales and customer support capabilities, commensurate with our growth objectives."
Martin Haase, President and CEO of Bruker AXS and Senior Vice President of Bruker BioSciences, commented: "We believe this restructuring is an important step towards improved efficiency of operations at Bruker BioSciences. This plan is expected to reduce our fixed cost of operations as well as overhead costs significantly, and is designed to improve our gross and operating margins. We maintain our strong focus on R&D and product innovation, which is the key to our future top- and bottom-line growth."
ABOUT BRUKER BIOSCIENCES
Bruker BioSciences Corporation, headquartered in Billerica, Massachusetts, is the publicly traded parent company of Bruker AXS Inc. and Bruker Daltonics Inc. Bruker AXS is a leading developer and provider of life science and advanced materials research tools based on X-ray technology.

News on www.julabo.de
The improved version, of the free of charge control software ‚EasyTemp‘ is now available. Please download by using the link below:
http://www.julabo.de/jgmbh/english/software.htm

Interesting things about JULABO

I. Modern development in production and engineering
Worldwide JULABO has a reputation for highly innovative products. To continue this reputation of high quality products, JULABO counts on the most modern development and production engineering. In JULABO’s research and developmental department, highly qualified engineers and technicians are continually working on temperature solutions for the future. Starting from the PC-simulation up to software programming, everything is realized in-house. For this, the most up-to-date development systems and 3D-CAD workplaces are available. Additionally, JULABO has an automated environmental friendly production with CNC machines, powder coating, as well as a production of circuit boards.

II. Tested quality
As one of the first companies in Germany, JULABO has established a quality management, according to ISO 9001:2000 standard. Each of the units manufactured by JULABO meet the highest national, European and international standard. In all stages of production the individual parts are subjected to numerous tests, as well as the tests run on the completed unit:

- Material-/functional testing on all parts used;
- Computer assisted examination of the electronic components;
- Functional/visual checking during the assembly;
- Electrical safety check according to VDE;
- 100% final checks with endurance tests running for each unit;
- Documentation and traceability according to ISO.

Special: Win a SONY digital camera
You have 5 minutes to gather information about the new circulators, using the interactive Demo CD-ROM. This CD also includes a lottery quiz with a monthly raffle for a 'SONY Cybershot DSC-P52‘ digital camera. To participate in this quiz, answer five easy questions. Order your personal copy, free of charge now!

News, press, catalogues
Special publications, have produced different articles highlighting the new circulator program. One of these, 'Laborpraxis', gave a report in their September edition .
Please read this article by clicking on the link below:
http://www.julabo.de/newsletter/3-2003/pr006_e.pdf

Latest Edition: New circulator program
Heating and Refrigerated Circulators for liquid temperature application are essential for various applications in today’s market. Everywhere laboratory circulators are needed for research, material tests, production plants, experimental set-ups etc. With the NEW Circulator program JULABO offers more than 100 new models, with many solutions to aid everyday life. The new developments offer MORE features and benefits for similar prices.

Advantages:

- Up to 96% extra pump capacity;
- Pump capacity electronically adjustable;
- Early warning system for low level;
- Three-point calibration;
- Bright VFD Comfort Display;
- Temperature Control Features;
- Online communication with RS232, USB etc.;
- Integrated programmer with real-time clock
and much much more
Interested?
You can get the NEW brochure, Circulators/Baths 2003, free of charge from JULABO or as PDF-download off the internet.

Places to contact for a free brochure and/or information:
Phone (+49) 78 23 / 51-0, Fax (+49) 78 23 / 24 91
Email info@julabo.de

Spare parts quickly and easily via the Internet.
Please find the catalogue for accessories with description and pictures on our homepage.

New exclusive representative in South Africa.
In order to succeed in new markets we have an exclusive distributor since July 2003 in South Africa, company ADI Scientific (Pty) Ltd., Advanced Laboratory Solutions.

NanoSTAR - Enter the Universe of Nanostructure Analysis

The new NanoSTAR, the innovative small angle X-ray scattering system is the ideal tool to investigate precipitants in bulk materials and macromolecules in e.g. solutions with a size in the order of 10 to 1000 Angstroem.

Features:
Versatile experimental platform for nanostructure analysis due to flexible sample handling and adjustable beam path conditions.

Wide range of applications for analysis of polymers, biological materials, fibres, metals, nanopowders, complex fluids, etc.

Analysis of sizes, size distributions, shapes and orientation distributions in liquids, powders or bulk samples.

Efficient solution for scientists as well as researchers requiring fully automated measurements.
- All in one instrument :nanostructure analysis by means of Small Angle X-ray Scattering (SAXS);
- nanostructure mapping with scanning SAXS / X-ray radiography;
- molecular structure determination by Wide Angle X-rayScattering (WAXS).

The NanoSTAR is a joint project of: Bruker AXS, Institute of Chemistry at the University of Aarhus in Denmark, Max Planck Institute of Colloids and Interfaces, Department of Biomaterials in Potsdam, Germany and Material Competence Centre Leoben in Austria.

Use of the new Spinning Drop Tensiometer SITE100 for characterization of critical micelle concentrations.
The stability of emulsions is to a large extent determined by interfacial properties of the participating phases, and their storage stability can be optimized by the use of emulsifiers to lower the interfacial tension. This is made possible by the fact that the reduction in the interfacial tension lowers the driving force for separating the oil and water phases. The optimum adjustment of the necessary amount at a particular temperature depends on the diffusion rate at the interfacial boundary and the critical micelle concentration, among other things.

The Washburn "C" Factor for characterization of porous coatings.
Porous coatings find application in a wide variety of industrial, military, and medical applications. For example, porous photo and electro catalytic coatings are used in applications ranging from chromate production to cyanide destruction - and are also being explored for use in air and water treatment. In the medical field, porous coatings are used on the surface of replacement joints to promote a stable bone-implant interface by providing support for both ingrowth and ongrowth. Porous coatings are also widely used to support various reagents for blood and plasma analysis on diagnostic strips and slides.