Discovery Partners International, Inc. and Bruker AXS Inc. Announce Strategic Alliance and Distribution Agreement

SAN DIEGO and MADISON, Wis., July 25 /PRNewswire-FirstCall/ -- Discovery Partners International, Inc. (Nasdaq: DPII) and Bruker AXS Inc., a subsidiary of Bruker BioSciences Corporation (Nasdaq: BRKR) announced today that they have entered into a significant multi-year strategic alliance. Under the terms of the agreement, Discovery Partners and Bruker AXS will collaborate to provide seamless integration of systems for protein crystallization and X-ray crystallography for structural proteomics applications. Effective immediately, Bruker AXS will become the worldwide distributor for Discovery Partners' Crystal Farm(TM) line of protein crystallography products. Financial terms of the agreement were not disclosed.
Discovery Partners' Crystal Farm(TM) is the first commercially available integrated incubation and imaging system for protein crystallization to be offered to the Proteomics community. By providing high throughput protein crystallization automation, Crystal Farm(TM) is addressing the critical drug discovery quest for high-speed structure based drug design. This system combines capacity for up to 40,000 simultaneous experimental conditions, with DPI's patent pending "Cool Flash" imaging technology, and includes a web- browser based interface that controls all system functions either locally or remotely, including priority-based image scheduling, viewing and scoring. Experimental results stored in a SQL database can be easily mined for monitoring crystallization experiments

Latest From the Denver conference

D8 FOCUS – Your Dedicated Performer for Powder Diffraction*
(* for the time being only available in USA and Canada)

The D8 FOCUS is our new attractively priced entry-level system for powder diffraction applications. Based on the proven D8 Series II technology, the D8 FOCUS continues the high quality standards of Bruker AXS and is upwardly compatible

Applications:
Qualitative phase analysis
Quantitative phase analysis
Structure solution and refinement
Crystallite size determination
Microstrain analysis

Features:
Parallel beam geometry for irregularly shaped samples and high- and low temperature measurements
Bragg-Brentano geometry for standard powder samples

Quick exchange of optics and sample holders without tools and without realignment.

Leading software with superior full-pattern search
Choice of detectors: scintillation counter, Sol-X, and position sensitive detector (PSD) to be exchanged without realignment

Again we are happy to present numerous new products from KRUSS. Let us highlight two products here: The DSA100 represents the new generation of contact angle measuring systems that comes with revolutionary new features. The DSA10HT on the other hand allows you to measure contact angles on glasses, metals and alloys at temperatures up to 1900°C.

Also we have changed a lot in the way we present ourselves towards you and all our customers. We are proud to present our Online Shop and our new Web-Design. The Online Shop allows you to try out our new bubble pressure tensiometer PocketDyne in a virtual manner with plenty of information at your finger tips and gives you access to an easy and secured way for ordering the instrument.

We also underline just another time our claim to be the solution provider with our reports on new applications taken from industries that use our instrumentation. One of the things we show are first results from our new video supported Spinning Drop Tensiometer SITE100 for the measurement of very small interfacial tensions.

And we are especially happy to announce that KRUSS has been awarded as one of the TOP100 innovative medium-sized companies in Germany in 2003. We have officially received the award at a gala night on July 4 in Berlin which was hosted by Prof. Dr. h.c. Lothar Spath, former prime minister of Baden-Wurttemberg. We were awarded for outstanding achievements in innovation and creativity.

Introduction to online business
In the last few days it has become possible to purchase directly from KRUSS via the Internet. Initially you will find here the new PocketDyne Bubble Pressure tensiometer BP2100.

KRUSS homepage with a new appearance
In the last few days the German pages of the KRUSS homepage have appeared in a new design.

KRUSS GmbH honoured for innovative energy.
KRUSS GmbH has been honoured for its outstanding performances in the fields of innovation and creativity by being included as one of the TOP100 medium-sized companies in Germany.

DSA100/DSA100L - The new contact angle measuring system generation. Flexible sample size, flexible measuring technique – with its double modularity concept KRUSS GmbH has revolutionized contact angle measuring technology.

DSA10HT - The high temperature measuring system for contact angle measurements on glasses, metals and alloys at temperature up to 1900°C.

Use of the new Spinning Drop Tensiometer SITE100 for characterization of critical micelle concentrations.
The stability of emulsions is to a large extent determined by interfacial properties of the participating phases, and their storage stability can be optimized by the use of emulsifiers to lower the interfacial tension. This is made possible by the fact that the reduction in the interfacial tension lowers the driving force for separating the oil and water phases. The optimum adjustment of the necessary amount at a particular temperature depends on the diffusion rate at the interfacial boundary and the critical micelle concentration, among other things.

The Washburn "C" Factor for characterization of porous coatings.
Porous coatings find application in a wide variety of industrial, military, and medical applications. For example, porous photo and electro catalytic coatings are used in applications ranging from chromate production to cyanide destruction - and are also being explored for use in air and water treatment. In the medical field, porous coatings are used on the surface of replacement joints to promote a stable bone-implant interface by providing support for both ingrowth and ongrowth. Porous coatings are also widely used to support various reagents for blood and plasma analysis on diagnostic strips and slides.

NanoSTAR - Enter the Universe of Nanostructure Analysis

The new NanoSTAR, the innovative small angle X-ray scattering system is the ideal tool to investigate precipitants in bulk materials and macromolecules in e.g. solutions with a size in the order of 10 to 1000 Angstroem.

Features:
Versatile experimental platform for nanostructure analysis due to flexible sample handling and adjustable beam path conditions.

Wide range of applications for analysis of polymers, biological materials, fibres, metals, nanopowders, complex fluids, etc.

Analysis of sizes, size distributions, shapes and orientation distributions in liquids, powders or bulk samples.

Efficient solution for scientists as well as researchers requiring fully automated measurements.
- All in one instrument :nanostructure analysis by means of Small Angle X-ray Scattering (SAXS);
- nanostructure mapping with scanning SAXS / X-ray radiography;
- molecular structure determination by Wide Angle X-rayScattering (WAXS).

The NanoSTAR is a joint project of: Bruker AXS, Institute of Chemistry at the University of Aarhus in Denmark, Max Planck Institute of Colloids and Interfaces, Department of Biomaterials in Potsdam, Germany and Material Competence Centre Leoben in Austria.

Spare parts quickly and easily via the Internet.
Please find the catalogue for accessories with description and pictures on our homepage.

New exclusive representative in South Africa.
In order to succeed in new markets we have an exclusive distributor since July 2003 in South Africa, company ADI Scientific (Pty) Ltd., Advanced Laboratory Solutions.

Latest Edition: New circulator program
Heating and Refrigerated Circulators for liquid temperature application are essential for various applications in today’s market. Everywhere laboratory circulators are needed for research, material tests, production plants, experimental set-ups etc. With the NEW Circulator program JULABO offers more than 100 new models, with many solutions to aid everyday life. The new developments offer MORE features and benefits for similar prices.

Advantages:

- Up to 96% extra pump capacity;
- Pump capacity electronically adjustable;
- Early warning system for low level;
- Three-point calibration;
- Bright VFD Comfort Display;
- Temperature Control Features;
- Online communication with RS232, USB etc.;
- Integrated programmer with real-time clock
and much much more
Interested?
You can get the NEW brochure, Circulators/Baths 2003, free of charge from JULABO or as PDF-download off the internet.

Places to contact for a free brochure and/or information:
Phone (+49) 78 23 / 51-0, Fax (+49) 78 23 / 24 91
Email info@julabo.de

News, press, catalogues
Special publications, have produced different articles highlighting the new circulator program. One of these, 'Laborpraxis', gave a report in their September edition .
Please read this article by clicking on the link below:
http://www.julabo.de/newsletter/3-2003/pr006_e.pdf